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Getting to the Depot Inn is easy. . .
- Come by Rail:
Amtrak's Southwest Chief stops at the nearby depot twice each day, as it makes it's way from Chicago to Los Angeles, and back to Chicago again. Tell us that you're coming in on Amtrak and we'll pick you up. When it's time to go again, we'll take you to the depot for departure. - Come by Air:
The nearby Kirksville Regional Airport is serviced by U.S. Airways, offering flights to/from Kansas City and Chicago every day. Tell us that you're coming in on U.S. Airways and we'll pick you up. When it's time to go again, we'll take you back to the airport. Stress free, and easy. - Need a Car?
The Depot Inn is a concessionaire for Enterprise. Make your reservation in advance, and your car will be waiting for you at the hotel. Guests can also turn in the rental car at the hotel at the end of their stay. Make your Enterprise reservation today, and we'll pick you up. Access to last minute rentals also available.
Let Depot Inn be your home away from home for business travel and for leisure travel.

